脊椎肌肉缩与严重的超高位症:一个病例报告
Prachi Sharma1, Sham Lohiya1, Keta Vagha1
1Pediatrics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus
|March 11, 2024
概括
本病例报告详细介绍了第一个已知的脊柱肌肉缩 (SMA) 病例,该病例发生在患有严重高血压症的儿童身上. 这项研究强调了这种罕见的协会的临床表现和诊断过程.
科学领域:
- 神经学 神经学
- 遗传学 是一个遗传学.
- 儿科 儿科 儿科
背景情况:
- 脊柱肌肉缩 (SMA) 是一种遗传性自体递归性疾病,影响运动神经元,导致低血压和肌肉衰弱.
- 这种状况通常呈现出渐进的肌肉缩,主要是在下肢.
- 腰椎的过度向内曲,即高高师症,是一种明显的脊椎形.
相关概念视频
Herniated Intervertebral Disc l: Introduction
38
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
38
Degenerative Disc Disease I: Introduction
26
Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...
26
Degenerative Disc Disease ll: Pathophysiology
28
The symptoms of degenerative disc disease arise from a combination of mechanical compression, vascular compromise, and biochemical inflammation, which together disrupt nerve function and produce pain.Mechanical CompressionDisc degeneration reduces height and elasticity, predisposing to herniation of the nucleus pulposus, a major cause of radicular pain. Herniations may be protrusion (bulging with intact annulus), extrusion (nucleus extends beyond disc but remains connected), or sequestration...
28


