在单次注射Pegcetacoplancoplan后发生闭合性视网膜血管炎
Mariana Abi Karam1, Janet L Davis1, Stephen G Schwartz1
1Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Journal of vitreoretinal diseases
|March 11, 2024
概括
一个案例研究报告说,在一次内内注射佩格塞塔科普兰后,有视网膜血管炎. 这种罕见的并发症影响了一个80岁的老妇人,导致视力丧失和炎症.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 佩格塞塔科普兰是一种针对地理缩的向疗法.
- 静脉内注射是眼部药物输送的常见途径.
- 视网膜血管炎是一种严重的炎症状况,影响视网膜中的血管.
研究的目的:
- 为了记录一例视网膜血管炎的情况, pegcetacoplan 静脉内注射后.
- 为了突出与佩格塞塔科普兰治疗相关的潜在不良事件.
主要方法:
- 案例报告分析.案例报告分析.
- 临床检查和患者病史.
- 光素血管造影用于血管评估.
主要成果:
- 一名80岁的女性在注射后10天出现了症状.
- 视力敏度从20/80下降到20/150. 视力敏度从20/80下降到20/150. 视力敏度从20/80下降到20/150.
- 光素血管学揭示了严重的闭塞性血管炎,影响所有视网膜象限和斑点.
- 发炎和升高的眼内压力被注意到.
结论:
- 闭塞性视网膜血管炎可能发生在单次内注射佩格塞塔科普兰后不久.
- 这一案例表明,佩格塞塔科普兰与视网膜血管炎之间存在潜在的联系.
- 对这种不良事件进行进一步调查是有必要的.
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