比较柳科对成年人肥胖或不肥胖的死亡率的影响
Xiaorong Han1, Jinxing Liu1, Yingzhen Gu1
1Department of Special Care Center, Fuwai Hospital, National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167 Bei Li Shi Road, Xi Cheng District, Beijing 100037, China. amdangfw@163.com.
Food & function
|March 11, 2024
概括
这种药物是百合素 (Lycopene).
科学领域:
- 营养科学 营养科学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 百合素具有已知的抗炎和抗氧化特性.
- 肥胖是一个重要的公共卫生问题,与增加的死亡率有关.
- 了解不同健康状况的营养特异性影响至关重要.
研究的目的:
- 调查血清和饮食中胆水平与全因和心血管死亡率之间的关联.
- 为了确定这些关联是否在肥胖和没有肥胖的个体之间有所不同.
- 探讨利科与死亡结果的剂量反应关系.
主要方法:
- 对国家健康和营养检查调查 (NHANES) 数据 (2003-2006,2017-2018) 的分析.
- 包括11,737名成年人与死亡率数据的联系,平均随访时间为162个月.
- 调整了混因子的统计建模,以评估烯与死亡率的关系.
主要成果:
- 在非肥胖个体中,血清甘显示出"L"形的关联与所有原因的死亡率 (在低水平下有害,在值以上有保护作用) 和一致的心血管保护.
- 在肥胖个体中,血清白与所有原因死亡率 (低/高水平的风险,中间的保护) 呈现出"U"形的关联,以及心血管死亡率的类似模式.
- 在肥胖和非肥胖群体中,饮食中摄入的烯显示出对死亡率的保护作用.
结论:
- 莱科与死亡率的关联因肥胖状况而有很大差异.
- 血清白对死亡率的影响很复杂,在肥胖人群和非肥胖人群中观察到不同的模式.
- 个性化健康评估对于了解利科的益处至关重要,考虑到个体体重指数.
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