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希腊皮肤淋巴瘤的流行病学趋势

Stella Kaliampou¹, Vasiliki Nikolaou¹, Aikaterini Niforou²

¹1st Department of Dermatology and Venereology, Cutaneous Lymphoma Clinic, National and Kapodistrian University of Athens, "Andreas Sygros" Hospital of Venereal and Skin Diseases, Athens, Greece.

European journal of dermatology : EJD

|March 11, 2024

概括

希腊的初级皮肤淋巴瘤 (PCL) 发病率高于全球. 病率在2019年之前有所增加,可能是由于诊断更好,然后在COVID-19期间下降.

科学领域:

皮肤病学皮肤病学
在瘤学瘤学.
流行病学流行病学

背景情况:

初级皮肤淋巴瘤 (PCL) 是一种罕见的非霍奇金淋巴瘤,起源于皮肤.
全球PCL的流行病学数据有限.
了解PCL发病率和趋势对于公共卫生和资源分配至关重要.

研究的目的:

为了确定希腊阿提卡地区PCL的流行病学特征.
估计PCL及其亚型的年度发病率 (IR) 和时间趋势.
将希腊PCL发病率与国际数据进行比较.

主要方法:

在2009-2021年期间诊断出PCL患者的回顾性分析.
包括来自阿提卡一个主要的血液病理学转诊中心的1,189名患者.
计算每10万人/年的原始和经年龄调整的发病率.

主要成果:

总体PCL年度IR为每10万个人的2.2个新病例.
皮肤T细胞淋巴瘤 (CTCL) 占病例的82.3%,其中菌菌病 (MF) 是最常见的亚型 (68.7%).
在2019年之前,PCL,CTCL和MF的发病率上升,然后在2020-2021年下降,而皮肤B细胞淋巴瘤 (CBCL) 的发病率稳步增加. 希腊PCL的IR超过了国际上报告的IR.

结论:

希腊的PCL发病率明显高于其他地区.
诊断效率的提高可能解释了2020年之前的上升趋势.
COVID-19大流行可能导致了2020-2021年观察到的诊断下降.

关键词:

流行病学流行病学菌菌病菌病菌病一次性皮肤淋巴瘤.

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