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患有心血管疾病的妇女怀孕期间的电心图前节律变化
Constance G Weismann1,2,3, Frida Wedlund1,4, Thuva Lindblad Ryd1
1Clinical Sciences Lund, Lund University, Lund, Sweden.
Cardiology in the young
|March 11, 2024
概括
在患有先天性心脏病 (CHD) 的孕妇中,增加的QTc间隔与怀孕前的体重和心电图因子有关. 在怀孕期间密切监测心律失常对于这些高风险患者至关重要.
科学领域:
- 心脏病学 心脏病学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 电力生理学 电力生理学
背景情况:
- 怀孕会引起生理心血管变化,包括QTc间隔延长.
- 患有先天性心脏病 (CHD) 的孕妇面临心血管并发症的风险增加.
- 异常的QTc延长是潜在危及生命的腹腔失常的已知危险因素.
研究的目的:
- 确定与怀孕期间异常延长的QTc间隔相关的风险因素,在患有心脏病的妇女中.
- 调查妊娠期间绝对QTc持续时间 (>460毫秒) 和QTc间隔增加 (>27毫秒) 的预测因素.
主要方法:
- 一项回顾性,单中心研究分析了63名患有心血管疾病的妇女83次怀孕的数据.
- 人口和妊娠前心电图因素被评估为潜在的风险因素.
- 异常的QTc持续时间被定义为>460毫秒或从基线增加>27毫秒.
主要成果:
- 增加的QTc持续时间 (>460毫秒) 与更高的妊娠前QTc间隔,QRS持续时间,体重和体重指数相关.
- 增加QTc间隔 (>27毫秒) 与妊娠前心率升高有关.
- 在QTc变化和世界卫生组织 (mWHO) 修改的心血管风险分类或心血管疾病类型之间没有发现显著的关联.
结论:
- 怀孕前超重状态,心率较高和特定的心电图参数 (QTc,QRS持续时间) 与患有心脏病的孕妇的QTc间隔增加有关.
- 这些发现强调了怀孕期间在这个脆弱人群中对心律失常的警监测的重要性.
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