在急性肝炎中持续发烧:超出急性病毒性肝炎的范围
Arghya Samanta1, Ujjal Poddar1, Moinak Sen Sarma1
1Department of Pediatric Gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Infectious diseases (London, England)
|March 11, 2024
概括
区分热带感染与急性病毒性肝炎至关重要. 持续的发烧,皮疹和血栓塞缩症表明热带原因,而高胆红素和肝酶表明病毒性肝炎.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 肝病学 肝病学是一种肝病学.
背景情况:
- 急性肝炎在各种原因中呈现类似,包括热带感染和急性病毒性肝炎 (AVH).
- 区分这些疾病对于有效管理和减少发病率和死亡率至关重要.
研究的目的:
- 确定临床和实验室标记物,区分急性肝炎与热带感染与儿童的AVH.
- 在临床表现重叠的急性肝炎病例中提高诊断准确度.
主要方法:
- 从2013年1月到2023年3月对200名儿童 (150名患有AVH,50名患有热带感染) 的回顾性分析.
- 两组之间的临床特征,实验室调查,并发症和结果的比较.
主要成果:
- 甲型肝炎是最常见的AVH病因;热肠热,登革热,草皮伤寒和皮炎在热带感染中占主导地位.
- 持续发烧,皮肤皮疹,白血病和血小板减少在热带感染中更为频繁.
- 多变量分析发现,血小板缺血是热带感染的积极预测因子,高胆红素/透氨酶是热带感染的负面预测因子.
结论:
- 在患有黄后持续发烧的患者中,特别是在皮疹和血栓塞缩症患者中,对热带感染的高度怀疑指数是必要的.
- 较温和的黄,较低的透氨酶水平和血小板减少是热带感染引起的急性肝炎的关键指标.
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