[风湿性关节炎患者纤维肌痛的特征]
N A Melikova1,2, E G Filatova1, E S Filatova2
1Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
|March 11, 2024
概括
风湿性关节炎 (RA) 患者的纤维肌痛 (FM) 在生命的晚期发展. 虽然核心症状相似,但患有纯 FM 的患者报告生活质量较低,这突显了综合治疗方法的必要性.
科学领域:
- 类风湿病学 类风湿病学
- 疼痛医学 医学 疼痛医学
- 临床免疫学临床免疫学
背景情况:
- 类风湿性关节炎 (RA) 和纤维肌痛 (FM) 是经常同时发生的慢性疾病.
- 了解RA患者中FM的独特特征对于有效管理至关重要.
研究的目的:
- 在患有同时存在的类风湿性关节炎的患者中调查纤维肌痛的特征.
- 为了比较类风湿性关节炎和纤维肌痛 (RA+FM) 和原发性纤维肌痛 (FM) 患者之间的临床表现和生活质量.
主要方法:
- 一项涉及76名患者的研究,分为RA+FM (n=55) 和FM (n=21) 组.
- 收集的数据包括患者人口统计,疼痛综合征特征 (强度,表型),中心敏感症状,疲劳,焦虑,抑郁,睡眠质量,认知功能和生活质量.
主要成果:
- 与RA+FM患者相比,患有FM的患者在较晚的年龄被诊断出来.
- 虽然核心 FM 症状,疲劳和心理困扰是可比的,但患有初级 FM 的患者报告生活质量明显降低.
- 患有初级FM的患者经历了更长的诊断延迟,不太可能被认为是残疾人.
结论:
- 在 RA 患者中,纤维肌痛出现的年龄比原发性纤维肌痛晚.
- 无论RA是否同时发生,FM的初级临床表现都相似,但在初级FM中,生活质量明显较低.
- 将FM评估和管理整合到类风湿性疾病护理中,可以大大提高患者的生活质量.
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