在mRNACOVID疫苗接种后,广泛的反应性淋巴和脏FDG狂热症
Clinical nuclear medicine
|March 11, 2024
概括
在PET/CT上广泛存在的FDG激发性淋巴腺病变和脏吸收自发消失. 这种罕见的现象发生在COVID mRNA疫苗接种后不久,这表明存在潜在的联系.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 放射学 放射学是一门学科.
背景情况:
- 转移性肺腺癌需要谨慎监测.
- 用氧化葡萄糖 (FDG) 进行正子发射断层扫描/计算机断层扫描 (PET/CT) 对于监测治疗反应和检测复发至关重要.
- COVID-19 mRNA 疫苗接种与各种免疫反应有关.
研究的目的:
- 报告一个不寻常的广泛的FDG-avid淋巴结核病和脏吸收病例.
- 为了调查COVID-19 mRNA疫苗接种与此成像发现之间的潜在关联.
- 为了突出疫苗接种的罕见不良反应,模仿疾病进展.
主要方法:
- 一个75岁妇女肺腺癌缓解的病例报告.
- 监控PET/CT成像显示出意想不到的广泛的FDG贪.
- 短期随访PET/CT证明了FDG吸收的解决.
- 获得了详细的患者病史,包括最近的COVID-19 mRNA疫苗接种.
主要成果:
- 该患者在PET/CT上出现了新的,广泛的FDG-avid淋巴结核病和脏吸收.
- 没有发现局部复发或转移性疾病进展的证据.
- 在短时间的间隔内,在后续成像时,FDG热情显著下降.
- 症状的出现与患者的第五次COVID-19 mRNA疫苗剂量相吻合.
结论:
- 在COVID-19 mRNA疫苗接种后,广泛的,对称的FDG激发性淋巴腺病变和脏吸收可能是一种罕见的,短暂的反应.
- 这种成像发现可以模仿患有恶性瘤病史的患者的疾病复发或进展.
- 放射科医生和临床医生在解释FDG PET/CT扫描显示异常吸收模式时应考虑最近的疫苗接种史.
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