CD38CD4T,HIV

Fernando Díaz-Basilio1,2, Moisés Vergara-Mendoza3, Jessica Romero-Rodríguez4

  • 1Laboratory of Integrative Immunology, National Institute of Respiratory Diseases Ismael Cosío Villegas, Calzada de Tlalpan 4502, Tlalpan, 14080 Mexico City, Mexico.

PubMed
概括

通过限制代谢变化,CD38s酶活性限制了HIV中CD4 T细胞的反应. 抑制CD38恢复T细胞功能和新陈代谢,为HIV免疫病原发生提供了潜在的治疗点.

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