相关实验视频

Updated: Jul 1, 2025

Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model
12:23

Flow Cytometry Analysis of Immune Cell Subsets within the Murine Spleen, Bone Marrow, Lymph Nodes and Synovial Tissue in an Osteoarthritis Model

Published on: April 24, 2020

19.6K

骨关节炎的突性巨细胞的转录组分析显示了被容忍的表型,由弱的皮质类固醇反应加剧

Cheng Wang1, Ruben De Francesco1,2, Lieke A Lamers1

  • 1Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands.

Rheumatology (Oxford, England)
|March 11, 2024
PubMed
概括

骨关节炎巨细胞对皮质类固醇的反应有限,这可能解释了为什么这些治疗方法长期失败. 这种受限的反应表明,骨关节炎的关节巨体中存在潜在的炎症状态.

关键词:
皮质类固醇是什么细胞因子和化学因子.免疫力麻 免疫力麻巨细胞是什么?巨细胞是什么?骨关节炎是一种关节炎.有关突炎的炎症.

更多相关视频

Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue09:18

Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue

Published on: February 24, 2023

7.4K
Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs12:44

Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs

Published on: January 27, 2023

3.8K

相关概念视频

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
1.0K