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Updated: Jul 1, 2025

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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在Gαi蛋白中的多基区域:相关还是不相关? 来自Gαi3研究的见解

Beata Rysiewicz1, Ewa Błasiak1, Marta Dziedzicka-Wasylewska1

  • 1Department of Physical Biochemistry, Faculty of Biochemistry Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, Poland.

Cellular signalling
|March 11, 2024
PubMed
概括

Gαi3的多基区域对于其与多巴胺D2受体的空间布局及其抑制功能至关重要,即使没有显著影响细胞膜局部化. 非脂质Gαi3与负电荷的脂质相互作用,受膜流动性的影响.

关键词:
多巴胺D(2) 受体受体在GPCR中,GPCR是指GPCR.Gαi(3) 的一个子单位.异构三元的G蛋白质.细胞内部的cAMP水平.多基基图案多基基图案蛋白质-脂质相互作用

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