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Updated: Jul 1, 2025

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
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FASN通过通过Thr254的酸化和Pin1的异构化来降低p65表达的稳定性来负面调节p65表达

Lincoln Barlow1, Sophia Josephraj2, Boqing Gu2

  • 1Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, IN, USA.

Journal of lipid research
|March 11, 2024
PubMed
概括

脂肪酸合成酶 (FASN) 通过酸化调节p65蛋白的稳定性,这种过程由其产物palmitate介导. 这一发现揭示了癌症药物耐药性机制.

关键词:
这就是FASN.在 NF-κBB 中.一个Pin1一个Pin1异构化的异构化p6565 这是一个很好的方法.酸化的方法是光化.蛋白质酶体蛋白质组是什么

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