非过敏性鼻病:对分类,诊断和治疗的全面审查
Fuad M Baroody1, Philippe Gevaert2, Peter K Smith3
1Section of Otolaryngology-Head and Neck Surgery, University of Chicago Medicine, Chicago, Ill.
The journal of allergy and clinical immunology. In practice
|March 11, 2024
概括
非过敏性鼻炎 (NAR),通常称为血管运动性鼻炎,涉及鼻腔过敏反应. 了解其神经源途径和刺激物和天气等触发因素是有效诊断和治疗的关键.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏和免疫学 过敏和免疫学
- 神经科学是一个神经科学.
背景情况:
- 慢性非过敏性鼻炎 (NAR) 是一种常见的疾病,血管运动性鼻炎是最常见的亚型.
- NAR的特点是通过各种感官受体和短暂受体潜力 (TRP) 通道,由环境因素引发的症状.
- 准确诊断NAR是至关重要的,因为其复杂的分类,并发症,和不有效的治疗的风险.
研究的目的:
- 为提供对非过敏性鼻炎 (NAR) 亚型的全面概述.
- 澄清NAR的分类,诊断和治疗策略.
- 突出了解NAR病理生理学的重要性,以改善患者的治疗结果.
主要方法:
- 关于非过敏性鼻炎 (NAR) 的当前文献的综述.
- 对NAR的诊断标准和分类系统的分析.
- 评估治疗干预措施,包括环境,药物和手术选择.
主要成果:
- 血管运动鼻炎是NAR的主要形式,通常是由对TRP通道起作用的环境刺激引发的.
- 暂时受体潜在化物1 (TRPV1) 在NAR病理生理学中起着重要作用,其下调提供症状缓解.
- NAR经常与过敏性鼻炎 (混合鼻炎) 和喘和睡眠障碍等其他疾病共存.
结论:
- 准确的诊断和量身定制的治疗对于非过敏性鼻炎 (NAR) 的有效治疗至关重要.
- 了解神经发生机制和感官受体参与NAR可以改善治疗策略.
- 解决与NAR相关的并发症对于全面的患者护理和减少医疗保健负担至关重要.
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