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Updated: Jul 1, 2025

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STAT3通过防止有害的自身克林I型干扰素反应的激活来保护造血干细胞

Bhakti Patel1, Yifan Zhou1, Rachel L Babcock1,2

  • 1Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Leukemia
|March 12, 2024
PubMed
概括

信号转换器和转录3激活器 (STAT3) 防止了造血干细胞 (HSC) 中有害的干扰素反应,维持了它们的功能. STAT3抑制需要特定的向来保护健康的干细胞.

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