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Updated: Jul 1, 2025

Scalable Biomanufacturing Workflow to Produce and Isolate Natural Killer Cell-Derived Extracellular Vesicle-Based Cancer Biotherapeutics
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一个多功能工程外细胞囊平台,同时向和消除衰老的树皮细胞和瘤细胞,以促进瘤回归

Liangzhi Gong1, Zhengsheng Chen1, Kai Feng1

  • 1Institute of Microsurgery on Extremities, Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.

Journal of nanobiotechnology
|March 12, 2024
PubMed
概括

这项研究引入了工程化细胞外囊泡 (uPA-sEVs-siSrc),可以输送Src siRNA,以消除衰老的 stromal 细胞和瘤细胞. 这种双重作用疗法增强了化疗.

关键词:
细胞衰老 细胞衰老化疗 化疗是一种化学疗法.小小的细胞外囊泡.干细胞是干细胞的细胞.siRNA 是一个RNA.

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