牙位置,支和能力与认知衰退和发病性痴呆症的关联
Sam Asher1, Anna Liisa Suominen1,2,3, Ruth Stephen3,4,5
1Institute of Dentistry, University of Eastern Finland, Kuopio, Finland.
Journal of clinical periodontology
|March 12, 2024
概括
后期失去牙和减少能力显著增加痴呆症风险. 维持后闭塞支对于认知健康和预防认知衰退至关重要.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 牙科医学 牙科医学
背景情况:
- 新兴的研究将牙损失与认知障碍联系起来.
- 之前的研究还没有全面评估前后牙损失,闭塞支持和能力对认知的明显影响.
研究的目的:
- 调查后关闭支损失,牙损失和能力与认知功能和痴呆风险之间的关联.
- 为了区分前和后牙损失对认知衰退的影响.
主要方法:
- 使用2000年和2011年健康调查的数据进行横截面和纵向分析.
- 研究了与基线认知,11年认知衰退和15年事件痴呆风险的相关性.
主要成果:
- 后关闭支持损失显著增加了痴呆症风险 (HRs 1.992.89).
- 不足够的后关闭支持与整体认知能力下降和直接和延迟回忆能力受损有关.
- 后期牙损失与痴呆症有关 (HR 2.23),以及随着立即回忆能力的下降而减少的能力 (OR 1.80).
结论:
- 后牙和形支损失是痴呆症的重要危险因素.
- 后闭塞支损失的影响似乎依赖于剂量,并且独立于假牙的使用.
- 牙科专业人员应优先考虑后牙健康;建议对潜在机制进行进一步研究.
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