下四角眼与垂体腺瘤相关,以及视神经过度曲的潜在机制
Munehiro Demura1, Yasuo Sasagawa1, Yasuhiko Hayashi2
1Department of Neurosurgery, Kanazawa University, Kanazawa, Ishikawa, Japan.
Surgical neurology international
|March 12, 2024
概括
在垂体腺瘤中异常的视野缺陷可能源于视觉神经在视通道的压缩. 这项研究显示,视野缺陷较差的患者的视神经曲角度更大,这表明与瘤位置的联系.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 放射学 放射学是一门学科.
背景情况:
- 垂体腺瘤通常会导致上下视野缺陷.
- 非典型的较低视野缺陷的病因仍然不完全理解.
研究的目的:
- 为了调查下垂体腺瘤患者非典型的较低视野缺陷的潜在原因.
- 为了将视野缺陷模式与磁共振成像 (MRI) 发现的视神经压缩相关联.
主要方法:
- 对220名垂体腺瘤患者进行视野评估.
- 手术前的视野被分为典型的 (上方四角视) 或非典型的 (下方四角视).
- 核磁共振 (MRI) 评估了瘤特征和视神经压缩,重点关注视神经在视通道出口处曲的程度.
主要成果:
- 在440只眼睛中,有174只眼睛 (39.5%) 呈现视野缺陷.
- 在11名患者 (6.3%) 观察到非典型的较低视野缺陷.
- 视神经曲的程度在非典型组 (42.6°) 与典型组 (23.9°,P = 0.046) 相比显著增加.
结论:
- 在视通道出口的上边缘的视神经压缩可能导致一些垂体腺瘤的劣视场缺陷.
- 在诊断异常视野缺陷的患者的差异诊断中应考虑垂体腺瘤.
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