发性心肌炎与SARS-CoV-2感染:从案例研究中叙述性审查
Ryohei Ono1, Togo Iwahana1, Kaoruko Aoki1
1Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan.
概括
全发性心肌炎是SARS-CoV-2感染的严重并发症. 大多数患者需要机械循环支持,但85.5%的幸存者恢复了正常的心脏功能.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 临界护理医学 临界护理医学
背景情况:
- 肌心炎是SARS-CoV-2感染的严重并发症.
- 在SARS-CoV-2患者中,发性心肌炎的特征尚不清楚.
研究的目的:
- 系统地审查和描述与SARS-CoV-2感染相关的发性心肌炎病例.
主要方法:
- 对108例与SARS-CoV-2感染相关的发性心肌炎报告的系统审查 (2020年1月 - 2022年12月).
- 分析患者人口统计学,并发症,左心室喷射分数 (LVEF),包括机械循环支持 (MCS) 在内的治疗方法和结果.
主要成果:
- 受影响患者的平均年龄为34.8岁,男性占主导地位 (67/108).
- 93%的人出现心力衰竭,排气率降低 (LVEF ≤40%).
- 大多数患者 (97.8%) 接受了儿科胺,而62%需要MCS (主要是体外膜氧化).
- 总体死亡率为22.4%,但有可用的随访数据显示,85.5%的幸存患者心脏功能恢复正常.
结论:
- 在SARS-CoV-2感染的发性心肌炎中,主要影响年轻男性,并且经常呈现出严重的左心室功能障碍.
- 虽然需要密集的支持,但绝大多数幸存者经历了良好的心脏恢复.
相关概念视频
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Myocarditis I: Introduction
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Myocarditis III: Medical Management
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Myocarditis IV: Nursing Management
Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
Pericarditis I: Introduction
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...


