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需要机械通风的严重肝衰竭患者的结果:一个回顾性,单中心研究
Atsuyoshi Mita1, Sari Shimizu1, Takashi Ichiyama1
1Intensive Care Unit, Shinshu University Hospital Shinshu University School of Medicine Matsumoto Japan.
Health science reports
|March 12, 2024
概括
在等待移植的严重肝衰竭患者中,机械呼吸并没有增加90天的死亡率. 这种生命支持疗法是改善这一高风险人群的结果的可行选择.
科学领域:
- 关键护理医学 关键护理医学
- 肝病学 肝病学是一种肝病学.
- 移植手术 移植手术
背景情况:
- 肝衰竭的重症患者面临高死亡率.
- 肝移植是绝对的治疗方法,但由于预后不佳,机械通风的使用受到争议.
研究的目的:
- 研究等待移植的肝功能衰竭患者的重症监护和机械呼吸支持的结果.
- 评估机械呼吸对90天死亡率和肝移植资格的影响.
主要方法:
- 在ICU (2014-2020) 中32名肝衰竭患者的回顾性单中心研究.
- 分析包括APACHE-II和MELD得分,90天死亡率和使用Kaplan-Meier的生存率.
- 机械通风和非机械通风患者之间的结果比较.
主要成果:
- 平均年龄45.5岁,53%是女性;ICU入院APACHE-II和MELD分数分别为20和28.
- 13名患者 (40.6%) 接受机械呼吸;13名符合条件的患者中有4名接受了移植.
- 在通风 (61.5%) 和非通风 (47.4%) 组之间,90天死亡率相似 (p=0.4905).
- APACHE-II评分>21预测机械通风需要.
结论:
- 机械呼吸不会对严重肝衰竭患者的90天死亡率或肝移植率产生负面影响.
- 临床医生应该考虑机械通风作为等待移植的这些患者的生命支持选择.
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