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对于BAFF引发慢性淋巴细胞白血病的未被认可的细胞存活独立作用

Md Ashik Ullah1, Beatriz Garcillán2, Eden Whitlock1

  • 1Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute, Cancer Program, Herston, QLD, Australia.

Frontiers in immunology
|March 12, 2024
PubMed
概括

B细胞激活因子 (BAFF) 对于启动慢性淋巴细胞白血病 (CLL) 的关键是通过激活促进瘤基因,而不仅仅是细胞存活. 抑制BAFF可以通过减少瘤负担来增强CLL疗法.

关键词:
4月份的时间.巴夫 (BAFF) 是一个巴夫.在TCL1-Tg小鼠模型中慢性淋巴细胞白血病 慢性淋巴细胞白血病白血病的传播.白血病发病的开始.

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