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Updated: Jul 1, 2025

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
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双特异性自身抗原-T细胞参与剂作为针对自身反应性B细胞枯竭在自身免疫性疾病的向免疫治疗

Luca Perico1, Federica Casiraghi1, Fabiane Sônego2

  • 1Department of Molecular Medicine, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Bergamo, Italy.

Frontiers in immunology
|March 12, 2024
PubMed
概括

一种新型疗法,双特异性AutoAntigen-T细胞参与剂 (BiAATEs),针对自身免疫性疾病中的特定自身反应性B细胞. 这种方法对精确的,现成的治疗方法有希望,可能会彻底改变自身免疫性疾病的管理.

关键词:
对抗PLA2R的抗体.自身免疫性疾病 自身免疫性疾病自主反应的B细胞.双特异性自抗原-T细胞参与者.膜性脏病是一种膜性脏病.有针对性的免疫疗法.

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