持续负荷运动和高强度间歇训练对喘患者的缓解药物消耗和呼吸流量峰值的影响:一项随机对照试验
Ronaldo Aparecido da Silva1, Alberto Cukier2, Regina Maria Carvalho-Pinto2
1Department of Physical Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.
ERJ open research
|March 12, 2024
概括
高强度间歇训练 (HIIT) 和持续负荷运动 (CLE) 都减少了喘患者的短效β2-激动剂 (SABA) 使用. 然而,只有HIIT显著改善了峰值呼气流 (PEF) 和喘控制.
科学领域:
- 运动生理学 运动生理学
- 呼吸系统药物 呼吸系统药物
- 临床研究是临床研究.
背景情况:
- 有氧训练对喘患者的缓解药物使用和肺功能的影响尚不清楚.
- 对于这些结果,一直负载运动 (CLE) 和高强度间歇训练 (HIIT) 之间的直接比较以前没有被研究过.
研究的目的:
- 为了比较CLE与HIIT对短效β2-激动剂 (SABA) 消费和喘患者接受运动计划的喘患者的峰值呼气流 (PEF) 改善的影响.
主要方法:
- 临床稳定的喘参与者被随机分配到CLE (70-85%Wmax) 或HIIT (80-140%Wmax) 组进行12周的计划 (每周2次,每次40分钟).
- 峰值呼气流量 (PEF) 在每次会议前/后都被测量,如果PEF<70%,SABA使用就会触发.
- 喘控制问卷 (ACQ) -6,心肺运动测试 (CPET) 和有氧健身被评估为干预前/后.
主要成果:
- 无论是CLE还是HIIT都显著降低了SABA消费,只有1名参与者需要SABA干预后,而14名参与者需要SABA干预前.
- 虽然两组都改善了有氧健身和喘控制,但只有HIIT组在ACQ-6得分上显示出临床上有意义的改善.
- 运动后的PEF变化在HIIT组 (10.3±13.7%) 与CLE组 (1.6±25.3%) 相比显著更大.
结论:
- 无论是CLE还是HIIT都有效地减少了喘患者的SABA消耗.
- 在改善PEF和临床喘控制方面,HIIT显示出比CLE更优越的好处,这凸显了它在管理中度至重度喘方面的重要性.
- 运动训练,特别是HIIT,对于中度至重度喘患者至关重要.
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