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在印度早产和满期男婴中对小青春期的产后评估
Vijay Sheker Reddy Danda1, Krishna Reddy Thaduri2, Srinivas Rao Paidipally2
1Department of Endocrinology, Gandhi Medical College and Hospital, Secunderabad, Telangana, India. Correspondence to: Dr. Vijay Sheker Reddy Danda, Department of Endocrinology, Gandhi Medical College and Hospital, Musheerabad, Secunderabad, Telangana 500003, India. drdvsreddyendo@yahoo.com.
Indian pediatrics
|March 12, 2024
概括
印度早产的男性婴儿在迷你青春期表现出尿路素激素 (LH) 和丸激素的升高,阴茎长度和丸体积的增长速度比满期婴儿快.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 新生儿生理学 新生儿生理学
- 生殖健康 生殖健康
背景情况:
- 迷你青春期是婴儿早期发生的淋巴激素和激素分泌量升高的短暂阶段.
- 与满期婴儿相比,早产婴儿可能会经历内分泌发育的改变.
- 了解这些差异对于评估婴儿健康和发育至关重要.
研究的目的:
- 为了比较在印度早产 (PT) 和满期 (FT) 男婴中,在迷你青春期期间产后尿性淋巴腺素和丸激素分泌的时间和大小.
- 在此期间,研究PT和FT婴儿之间的身体生长参数的差异,例如伸展的阴茎长度 (SPL) 和丸体积 (TV).
主要方法:
- 一项前性观察性研究,涉及30名PT和60名FT的男性婴儿.
- 在多个时间点 (第7天,第1天,第2天,第4天和第6个月) 测量尿液质化激素 (LH),卵泡刺激激素 (FSH) 和水平.
- 与激素测量同时评估伸展的阴茎长度 (SPL) 和丸体积 (TV).
主要成果:
- 在第一个月,早产婴儿的尿液LH水平明显高于满期婴儿 (P < 0.001).
- 在PT婴儿中,丸激素水平显著升高 (P < 0.001),在第一个月内,SPL和TV的增加更大 (P < 0.001).
- 毛囊刺激激素 (FSH) 水平在第7天的PT婴儿中较低 (P < 0.001).
结论:
- 印度早产的男性婴儿在迷你青春期表现出尿路LH和丸激素的明显增加.
- 在此期间,早产婴儿表现出生殖器官 (SPL和TV) 的加速物理发育.
- 这些发现突出了早产男婴在早期发育过程中独特的内分泌和生长模式.
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