外基因组传递的波多普拉宁在质母细胞瘤中促进与瘤相关的巨细胞介导的免疫耐受性

Mengwan Wu1,2,3, Ying Shi1, Yuyang Liu4

  • 1Department of Oncology, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.

PubMed
概括

质母细胞细胞在细胞外囊泡 (EVsPDPN) 中释放波多普拉宁 (PDPN),促进免疫抑制M2巨细胞. 这种机制通过减少T细胞激活来阻碍免疫疗法,突出显示EVs作为治疗标.

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