梅波利祖马布在中国治疗严重酸性喘的成本效益
Xiong Chaogang1, An Mengna2, Wang Zhen3
1Department of Pharmacy, Xi'an Chest Hospital, Xi'an, Shaanxi Province, China.
概括
在中国,梅波利祖马布对于严重的酸性喘并非具有成本效益. 增量成本效益比率 (ICER) 超过支付意愿的门,需要大幅降低价格.
科学领域:
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 严重的乙酸性喘对健康造成重大负担.
- 梅波利祖马布为严重的酸性喘提供了向治疗的选择.
- 对医疗保健系统来说,评估新疗法的经济价值至关重要.
研究的目的:
- 评估梅波利祖马布作为在中国治疗严重酸性喘的附加疗法的经济价值.
- 为了确定与标准护理 (SoC) 相比,梅波利祖马布的增量成本效益比率 (ICER).
主要方法:
- 使用马尔科夫模型模拟患者一生的健康状况.
- 该模型结合了中国当地医疗保健成本和MENSA试验的疗效数据.
- 进行了敏感性和场景分析,以评估调查结果的可靠性和定价的影响.
主要成果:
- 梅波利祖马布加SoC与单独SoC的ICER估计为170,648.73美元/质量调整后生命年 (QALY).
- 敏感性分析证实了ICER的稳定性.
- 情景分析表明,需要降低82%的梅波利祖马布价格,才能达到中国38223.34美元/QALY的支付意愿门.
结论:
- 梅波利祖马布目前不是一个具有成本效益的医疗保健资源在中国的现有价格点.
- 高的ICER表明,目前的定价对于在中国医疗保健系统中广泛采用是不可接受的.
- 需要大幅降低价格才能使梅波利祖马布在中国被认为具有成本效益.
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