建立一个基础设施,以优化基因组学在研究中的整合:精确的健康需求评估结果
Caitlin G Allen1, Gwendolyn Bouchie1, Daniel P Judge1
1Medical University of South Carolina, Charleston, SC.
Translational behavioral medicine
|March 12, 2024
概括
将基因组学纳入翻译研究需要基础设施建设. 一项调查和采访确定了支持基因组学知情研究倡议的关键障碍和促进者.
科学领域:
- 基因组学就是基因组学.
- 翻译研究是翻译研究.
- 精确的健康 精确的健康
背景情况:
- 从历史上看,基因组学研究能力和资源是有限的.
- 最近的一项全人口基因组查计划强调了需要机构基因组学基础设施的需要.
- 整合基因组学对于推进翻译研究至关重要.
研究的目的:
- 评估研究人员对基因组健康的知识.
- 识别基因组学研究吸收的障碍和促进者.
- 为支持基因组学信息转化研究的战略提供信息.
主要方法:
- 一项调查对整个机构的36名研究人员进行了调查.
- 与8个不同的提供者和研究人员进行了定性访谈.
- 使用描述性统计数据分析了定量调查数据,并为主题分析编码了采访数据.
主要成果:
- 调查和采访主题揭示了对研究人员目前对基因组学的理解和需求的见解.
- 确定了障碍和促进者,为实施战略提供了路线图.
- 这些发现突出了将基因组学研究与精确健康倡议协调的机会.
结论:
- 开发强大的基础设施对于成功将基因组学整合到翻译研究中至关重要.
- 了解研究人员的观点是克服障碍和促进基因组学普及的关键.
- 这些发现为旨在利用基因组数据进行研究的机构提供了一个框架.
更多相关视频
09:34Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
33.8K
13:24Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
Published on: April 11, 2016
11.9K
相关概念视频
02:02Genomics
36.3K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.3K
01:29Issues And Trends In Healthcare Delivery System
5.6K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.6K
03:36Genome Annotation and Assembly
18.8K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
18.8K
03:00Next-generation Sequencing
88.8K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
88.8K