封装4-terpineol与β-cyclodextrin:包括机制,表征和相对湿度触发的释放
Chuanxiang Cheng1, Yujie Lei1, Tiantian Min1
1School of Agriculture and Biology & Bor S. Luh Food Safety Research Center & Shanghai Food Safety Engineering Center & Key Laboratory of Urban Agriculture, Shanghai Jiao Tong University, Shanghai 200240, China.
Food chemistry
|March 12, 2024
概括
这项研究详细介绍了β-cyclodextrin (β-CD) 如何与4-terpineol (4-TA) 形成包含综合体,从而提高其稳定性. 高湿度触发了这些复杂物中的4-TA的释放,显示了食品保存的潜力.
科学领域:
- 食品科学 食品科学 食品科学
- 化学 化学 化学
- 材料科学 材料科学 材料科学
背景情况:
- 单烯的4-Terpineol (4-TA) 具有宝贵的生物活性,但稳定性和溶解性不佳.
- β-cyclodextrin (β-CD) 封装是一种有希望的策略,通过形成包容复合体 (ICs) 来克服这些局限性.
研究的目的:
- 阐明4-TA中β-CD的纳入机制.
- 为了研究4-TA在包容复合物的形成过程中的行为.
- 评估该战略在食品保存应用中的潜力.
主要方法:
- 使用共同沉方法合成4-TA/β-CD纳入复合物.
- 对推动复杂物形成的相互作用 (键,疏水性相互作用) 的分析.
- 纳入模式的表征 (异基进入β-CD腔).
- 在不同相对湿度 (RH) 条件下评估4-TA释放特征.
主要成果:
- 成功合成了4-TA/β-CD纳入复合物的成功合成.
- 确定键和疏水相互作用是IC形成的关键.
- 确定4-TA的异基通过宽边进入β-CD腔.
- 证明高RH (85%和99%) 触发4-TA从ICs释放.
结论:
- 共同沉方法有效地形成了4-TA/β-CD纳入复合体.
- 纳入机制涉及特定的相互作用和4-TA在β-CD腔内的方向.
- 这项研究强调了囊括环极素的潜力,提高了4-TA的稳定性,并使其能够得到控制的释放,特别是在食品保存方面.
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