从热应激到缺氧的交叉适应:系统性审查和探索性元分析
Ashley G B Willmott1, Alicia G Diment2, Henry C Chung3
1The Cambridge Centre for Sport and Exercise Sciences (CCSES), Anglia Ruskin University, East Road, Cambridge, United Kingdom; Environmental Extremes Laboratory, University of Brighton, Eastbourne, East Sussex, United Kingdom; Para-Monte Altitude Awareness Charity, Eastbourne, East Sussex, United Kingdom.
Journal of thermal biology
|March 12, 2024
概括
热适应 (HA) 对休息期间的生理反应和在缺氧时的亚最大运动提供了适度的益处. 这种交叉适应策略可能有助于高度暴露有限的个体,尽管需要进一步研究.
科学领域:
- 环境生理学环境生理学
- 人类的适应能力
- 运动科学 运动科学
背景情况:
- 交叉适应 (CA) 描述了一个压力因素 (例如热量) 帮助另一个压力因素 (例如缺氧) 获得的生理益处.
- 了解热适应 (HA) 对低氧耐受性的影响对于特定人群至关重要.
研究的目的:
- 系统地审查和分析HA在休息和运动期间对生理,感知和性能结果的影响.
- 探索HA作为一个实际的适应策略的潜力.
主要方法:
- 来自Scopus和MEDLINE的研究的系统审查和元分析.
- 纳入标准侧重于人类参与者,具体干预措施和结果措施.
- 使用COSMIN检查清单进行质量评估.
主要成果:
- 对于休息时的氧和度 (g=0.60) 和下极限运动 (心率:g=-0.65,核心温度:g=-0.68,皮肤温度:g=-0.72) 的中度好处.
- 观察到通风 (g=0.24) 和最大运动性能 (峰值功率:g=0.32,计时试验:g=-0.43) 的小效应.
- 对感知结果没有显著的影响.
结论:
- 热适应对于在低氧条件下炼的人来说,显示出适度的生理益处.
- 对于高度暴露有限的职业或军事人员来说,HA可能是一个可行的替代方案.
- 需要对女性,训练有素的个体以及CA的潜在机制进行进一步的研究.
相关概念视频
Responses to Heat and Cold Stress
13.5K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
13.5K
Hypoxia
1.0K
Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
1.0K
Requirements for Human Life
8.2K
The Earth and its atmosphere have provided humans with air, water, and food, but these are not the only requirements for survival. Humans also require a specific range of temperature and pressure that the Earth and its atmosphere provides.
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
8.2K
Adaptations that Reduce Water Loss
25.6K
Though evaporation from plant leaves drives transpiration, it also results in loss of water. Because water is critical for photosynthetic reactions and other cellular processes, evolutionary pressures on plants in different environments have driven the acquisition of adaptations that reduce water loss.
25.6K
Positive and Negative Feedback Loops
19.1K
Animal organs and organ systems constantly adjust to internal and external changes through a process called homeostasis ("steady state"). Examples of these changes include regulation of the level of glucose or calcium in the blood or internal responses to external temperatures. Homeostasis requires maintaining an internal dynamic equilibrium:
19.1K
Acute Respiratory Failure-II
223
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
223


