TCMSSD:一个全面的数据库,专注于综合征标准化标准化
Lin Huang1, Qiao Wang2, Qingchi Duan2
1College of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, China; Key Laboratory of Chinese Medicine Rheumatology of Zhejiang Province, China.
概括
传统中医综合征标准化数据库 (TCMSSD) 为传统中医 (TCM) 综合征差异化研究提供了一个全面的资源. 它集成了大量的数据,并使用先进的算法来准确预测综合征.
科学领域:
- 综合医学是一个整体的医学.
- 计算生物学 计算生物学
- 传统中国医药 传统中国医药
背景情况:
- 关于传统中医 (TCM) 综合征差异化的标准化研究对于现代化TCM理论至关重要.
- 现有的数据库主要集中在草药处方的网络药理学上,对TCM综合征的差异化资源有限.
研究的目的:
- 为了弥补中医综合征差异化资源的缺口,开发了传统中医综合征标准化数据库 (TCMSSD).
- 该TCMSSD旨在为TCM综合征数据提供一个集中和标准化的平台.
主要方法:
- 该TCMSSD数据库是使用TCM文献和公共数据库 (TCMID,ETCM) 的数据构建的.
- 采用深度学习方法来构建数据库的知识图.
- 用于综合征预测功能的BM25算法.
主要成果:
- 该TCMSSD包含广泛的数据,包括624种综合征,133,518种处方,8,073种疾病和8,259种中国草药.
- 该数据库整合了关于43,413个成分,17,602个目标和8,182种药物的信息.
- 综合征预测工具分析输入数据与数据库对比,以根据已确定的模式生成预测.
结论:
- TCMSSD成功地填补了关键的空白,为定量和标准化的TCM综合征差异化研究提供了全面的资源.
- 这个数据库为未来对TCM综合征的生物学基础的研究奠定了基础.
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