植入的神经刺激的并发症:系统性审查和元分析
Roshini Kalagara1, Susmita Chennareddy1, Emma Reford1
1Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Cerebrovascular diseases (Basel, Switzerland)
|March 12, 2024
概括
用于中风康复的神经刺激 (VNS) 通常是安全的,具有轻微和暂时的副作用,如声. 进一步研究VNS用于中风恢复是有必要的,考虑到其已在其他条件下使用.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 医疗器械技术 医疗器械技术
背景情况:
- 神经刺激 (VNS) 显示出对缺血性中风康复的前景.
- 缺少VNS不良影响的全面总结,这对于知情同意至关重要.
- 本系统性审查和元分析解决了与VNS相关的并发症.
研究的目的:
- 系统地审查和分析与神经刺激 (VNS) 治疗相关的不良影响.
- 为考虑VNS的患者和临床医生提供关键的安全信息.
主要方法:
- 为了进行系统审查,遵循了PRISMA指南.
- 在主要的数据库 (Cochrane,Embase,Ovid MEDLINE) 中进行了搜索.
- 包括成人患者的前性随机对照试验;不包括病例研究或不完整的报告.
主要成果:
- 21项涉及1474名患者的研究符合纳入标准.
- 对,抑郁,焦虑,中风,心力衰竭和纤维肌痛的VNS进行了调查.
- 最常见的不良事件:声音变化 (45.5%),麻醉 (15.8%),咳 (15.0%),呼吸障碍 (14.3%),疼痛 (11.5%).
结论:
- 由VNS引起的并发症通常是轻微的和短暂的.
- 随着时间的推移,不良事件的严重程度和频率都会减少.
- 对于抗治疗性疾病来说,VNS仍然是一个可行的选择,并且在中风恢复方面需要进一步探索.
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