接受过导管大动脉置换与上升大动脉扩张的患者的结果
Dejing Feng1, Jie Zhao1, Guannan Niu1
1Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100037, China.
International journal of cardiology
|March 12, 2024
概括
过导管大动脉置换 (TAVR) 的结果在患有上升大动脉扩张 (AAD) 和没有上升大动脉扩张 (AAD) 的患者中类似. 这项研究发现,在接受TAVR的组之间,死亡率或大动脉扩张进展没有显著差异.
科学领域:
- 心脏病学 心脏病学
- 心血管外科心血管外科
- 干预心脏病学 干预心脏病学
背景情况:
- 大动脉狭窄 (AS) 是一种重要的心血管疾病.
- 上升性大动脉扩张 (AAD) 是AS患者接受TAVR的常见发现.
- AAD对TAVR结果的影响需要进一步调查.
研究的目的:
- 为了比较TAVR的短期和长期结果,在有和没有中度/严重上升大动脉扩张 (AAD) 的患者中.
- 为了评估TAVR后AAD的进展率.
主要方法:
- 一组556名接受TAVR治疗的严重AS患者被追溯分析.
- 患者被分为中度/重度AAD (≥45毫米) 和非/轻度AAD组.
- 使用卡普兰-梅尔曲线和日志等级测试来评估生存结果;CT数据分析了AAD进展.
主要成果:
- 107名患者 (19.2%) 患有中度至重度AAD.
- 两组之间医院内上升大动脉剖析没有显著差异 (1.9%对0.4%).
- 四年全因和心血管死亡率相似 (P=0.109和P=0.698).
- 两组之间AAD进展率没有显著差异 (P=0.122).
结论:
- 中度/重度AAD不会显著影响AS患者接受TAVR的短期或长期结果.
- 在TAVR后具有或没有基线中度/严重扩张的患者中,AAD进展没有显著差异.
- 无论上升大动脉直径如何,TAVR似乎是安全有效的.
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