与艾滋病毒相关的内马林肌病症表现为曲脊柱综合征
Ali Zagham Nasir1, Andrew Jameson2
1Internal Medicine Residency, Trinity Health Grand Rapids Hospital, Grand Rapids, Michigan, USA ali.nasir@trinity-health.org.
BMJ case reports
|March 12, 2024
概括
零星晚发性内马林肌病 (HIV-NM) 是一种导致艾滋病毒患者肌肉衰弱的疾病. 这一案例表明,即使在控制良好的HIV患者中,HIV-NM也可能发生,这强调了迅速诊断的必要性.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 类风湿病学 类风湿病学
背景情况:
- 与艾滋病毒相关的肌肉病是一组影响人类免疫缺陷病毒 (HIV) 患者的神经肌肉疾病.
- 零星晚发性尼马林肌病 (HIV-NM) 的特点是肌肉逐渐疲软,肌肉纤维中尼马林体的特定组织学发现.
研究的目的:
- 在长期接受ART治疗的HIV患者中呈现一种HIV-NM病例.
- 为了说明罕见的HIV-NM呈现与渐进性曲脊柱综合征 (camptocormia).
- 强调考虑HIV-NM在艾滋病毒患者中具有无法解释的肌肉骨症状的重要性.
主要方法:
- 案例报告的呈现方式.
- 对HIV-NM的临床表现,诊断发现和治疗进行审查.
- 讨论患者的长期艾滋病毒管理和ART坚持.
主要成果:
- 描述了一例长达数十年的,在ART治疗中得到良好控制的HIV患者的HIV-NM呈现为camptocormia的病例.
- 患者经历了与HIV-NM相一致的渐进式近道和轴向肌肉衰弱.
- 这一案例表明,即使在HIV有效管理的患者中,HIV-NM也可能发生.
结论:
- 应考虑HIV-NM在HIV患者的渐进性肌肉衰弱和肌肉骨疾病的差异诊断中,无论病毒载量或ART状态如何.
- 早期识别和诊断HIV-NM对于适当的管理至关重要.
- 这一案例强调了艾滋病毒相关肌肉病变的多样化临床表现.
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