相关实验视频

Updated: Jul 1, 2025

Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay
11:22

Quantitative Analysis of Alternative Pre-mRNA Splicing in Mouse Brain Sections Using RNA In Situ Hybridization Assay

Published on: August 26, 2018

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综合转录组分析揭示了老老鼠大脑中改变的mRNA拼接和转录后变化

Nisha Hemandhar Kumar1, Verena Kluever1, Emanuel Barth2,3

  • 1Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, 37073 Göttingen, Germany.

Nucleic acids research
|March 12, 2024
PubMed
概括

研究老年小鼠大脑中的mRNA拼接揭示了与年龄相关的基因表达和RNA处理的变化. 这些发现对于理解大脑衰老和制定对抗认知衰退的策略至关重要.

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Analysis of Translation in the Developing Mouse Brain using Polysome Profiling08:38

Analysis of Translation in the Developing Mouse Brain using Polysome Profiling

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相关概念视频

RNA Splicing01:32

RNA Splicing

Splicing is the process by which eukaryotic RNA is edited before its translation into protein. The RNA strand transcribed from eukaryotic DNA is called the primary transcript. The primary transcripts that become mRNAs are called precursor messenger RNAs (pre-mRNAs). Eukaryotic pre-mRNA contains alternating sequences of exons and introns. Exons are nucleotide sequences that code for proteins, whereas introns are the non-coding regions. In RNA splicing, introns are removed and exons are bonded...
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