Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Nociception01:44

Nociception

27.9K
Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
27.9K
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

4.4K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
4.4K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

956
Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
956
Inflammatory Response01:28

Inflammatory Response

2.0K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
2.0K
Sympathetic Pathways: Sympathetic Chain Ganglia01:21

Sympathetic Pathways: Sympathetic Chain Ganglia

2.5K
The sympathetic chain ganglia, also known as the sympathetic trunk ganglia or paravertebral ganglia, are a series of ganglia located bilaterally on either side of the spinal column. These ganglia serve as relay stations for the sympathetic nervous system. Preganglionic neurons originating in the spinal cord project their axons to the sympathetic chain ganglia. Within the ganglia, these preganglionic fibers synapse with postganglionic neurons.
The postganglionic neurons of the sympathetic trunk...
2.5K
Somatosensation01:33

Somatosensation

36.6K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
36.6K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Antibodies in immune-mediated peripheral neuropathies. Where are we in 2024?

Revue neurologique·2024
Same author

Intravenous immunoglobulin for treatment of chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy in France: are daily practices in accordance with guidelines?

European journal of neurology·2018
Same author

Lethal form of spinocerebellar ataxia type 7 with early onset in childhood.

Archives de pediatrie : organe officiel de la Societe francaise de pediatrie·2017
Same author

Somatosensory evoked potentials in the assessment of peripheral neuropathies: Commented results of a survey among French-speaking practitioners and recommendations for practice.

Neurophysiologie clinique = Clinical neurophysiology·2015
Same author

Pathophysiology and biomarkers in chronic inflammatory demyelinating polyradiculoneuropathies.

Revue neurologique·2014
Same author

[Editorial].

Revue neurologique·2014
Same journal

Macrophage inclusions in patients undergoing antisense oligonucleotide therapy for ALS or SMA: A retrospective and transversal study.

Revue neurologique·2026
Same journal

Geographic disparities in MRI features of ischemic stroke and small vessel disease: A comparative study between French Guiana and mainland France. Findings from the BECATOUR multicenter registry.

Revue neurologique·2026
Same journal

Continuous subcutaneous perfusion of apomorphine in Parkinson's disease: Towards monotherapy?

Revue neurologique·2026
Same journal

Neuro-Whipple presenting as autoimmune encephalitis.

Revue neurologique·2026
Same journal

Multimodal assessment of minimally conscious state and cognitive motor dissociation in neurocritical care: A critical review.

Revue neurologique·2026
Same journal

Development of a new episodic memory assessment tool (NEM): Preliminary data and clinical perspectives.

Revue neurologique·2026
查看所有相关文章

相关实验视频

Updated: Jul 1, 2025

Author Spotlight: A Procedure for Mouse Dorsal Root Ganglion Cryosectioning
04:20

Author Spotlight: A Procedure for Mouse Dorsal Root Ganglion Cryosectioning

Published on: June 9, 2023

6.4K

炎症性感官神经病变 炎症性感官神经病变

J-C Antoine1

  • 1Department of Neurology, University Hospital of Saint-Etienne, 42055 Saint-Étienne cedex, France.

Revue neurologique
|March 12, 2024
PubMed
概括
此摘要是机器生成的。

早期识别炎症感官神经病变是关键. 及时的免疫调节治疗可以在发生不可逆转的神经损伤之前稳定或改善这些罕见的感觉神经元疾病.

关键词:
抗体是一种抗体.麻性神经系统综合征是什么?感觉性腺节病变是一种感觉性腺节病变.感官神经病变是一种神经病变.斯约格伦综合征是什么意思治疗方法 治疗方法

更多相关视频

Tissue Preparation and Immunostaining of Mouse Sensory Nerve Fibers Innervating Skin and Limb Bones
10:25

Tissue Preparation and Immunostaining of Mouse Sensory Nerve Fibers Innervating Skin and Limb Bones

Published on: January 26, 2012

23.2K
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
08:56

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

2.7K

相关实验视频

Last Updated: Jul 1, 2025

Author Spotlight: A Procedure for Mouse Dorsal Root Ganglion Cryosectioning
04:20

Author Spotlight: A Procedure for Mouse Dorsal Root Ganglion Cryosectioning

Published on: June 9, 2023

6.4K
Tissue Preparation and Immunostaining of Mouse Sensory Nerve Fibers Innervating Skin and Limb Bones
10:25

Tissue Preparation and Immunostaining of Mouse Sensory Nerve Fibers Innervating Skin and Limb Bones

Published on: January 26, 2012

23.2K
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
08:56

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies

Published on: October 7, 2021

2.7K

科学领域:

  • 神经学 神经学
  • 免疫学 免疫学 免疫学
  • 遗传学 遗传学 是一个

背景情况:

  • 炎症性感官神经病变是一种罕见的,异质的疾病,影响背部根性质感官神经元.
  • 这些疾病是由免疫不良机制引起的,并且可能与癌症,自身免疫性疾病 (如Sjögren综合征) 或病毒感染有关.
  • 很大一部分病例仍然是孤立的,缺乏明确的触发因素.

研究的目的:

  • 强调早期识别炎症感官神经病变的关键需要.
  • 通过及时的免疫调节治疗,突出疾病稳定或改善的潜力.
  • 强调生物标志物,特别是抗体在促进早期诊断和治疗试验开发中的作用.

主要方法:

  • 对有关炎症感官神经病变的现有文献的综述.
  • 对诊断标准和临床表现的分析.
  • 讨论免疫调节和免疫抑制疗法的作用.
  • 强调生物标志物发现,包括自身抗体.

主要成果:

  • 存在各种临床过程 (急性,亚急性,慢性) 的炎症性感官神经病变.
  • 早期诊断对于通过免疫调节或免疫抑制治疗进行有效干预至关重要.
  • 生物标志物,特别是抗体,对于早期识别和指导治疗策略至关重要.
  • 及时治疗可以预防最终的神经元退化,并改善患者的治疗结果.

结论:

  • 早期诊断炎症感官神经病变对于成功治疗至关重要.
  • 免疫调节疗法具有稳定或逆转疾病进展的潜力.
  • 开发和应用特定的生物标志物对于在这些罕见疾病中推进治疗策略和临床试验至关重要.