压力和catecholamines与儿童疼痛的TMD之间的联系
Claudia Restrepo-Serna1, Adriana Santamaría-Villegas1
1CES-LPH Research Group, Universidad CES, Medellín, Colombia.
International journal of paediatric dentistry
|March 13, 2024
概括
压力及其生物标记物,包括多巴胺,上腺素和上腺素,与儿童的关节障碍 (TMD) 疼痛有关. 这突出了理解和管理儿科TMD的潜在新途径.
科学领域:
- 儿科牙科 儿科牙科
- 生物标志物 生物标志物
- 神经科学是一个神经科学.
背景情况:
- 部部疾病 (TMD) 在儿童中很普遍,通常表现为肌筋部疼痛和头痛.
- 生物标志物如 катехоламин (多巴胺,上腺素,上腺素) 可能受到生活方式因素的影响,如屏幕时间和睡眠损失,可能预测TMD疼痛.
- 了解这些关联可以为儿科TMD开辟新的研究途径.
研究的目的:
- 为了研究压力,甲基荷兰胺和TMD相关的肌肌关节疼痛和儿童头痛之间的关系.
- 确定压力和特定生物标志物是否预测儿科TMD的疼痛症状.
主要方法:
- 一项涉及66名年龄在9-11岁的儿童的研究,根据TMD (DC/TMD) 诊断标准的第I轴,他们被诊断患有TMD.
- 使用感知压力尺度-儿童 (PSS-C) 评估感知压力.
- 通过液体染色学分析24小时尿液样本,以检测甲醇胺 (多巴胺,上腺素,上腺素) 含量,随后进行回归分析.
主要成果:
- 感知到的压力,多巴胺,上腺素和上腺素被确定为肌肌痛疼痛和头痛的显著预测因子,归因于TMD.
- 单变量和多变量后勤回归分析都证实了这些关联.
- 该研究包括了儿童,平均年龄为10.3岁,平均压力评分为29±4.
结论:
- 较高的压力水平和相关的生物标志物增加了患有TMD的儿童发展肌肌关节疼痛和头痛的可能性.
- 这些发现强调了在儿科TMD的背景下考虑心理压力和生理标记的重要性.
- 对压力管理和生物标志物监测的进一步研究可能为患有TMD的儿童提供新的治疗策略.
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