双甲状腺视神经病变中的轨道CT扫描参数:系统性审查和元分析
Thansit Srisombut1, Niracha Arjkongharn2, Nattaporn Vongsa2
1Department of Surgery, Sawanpracharak Hospital, 3 Attakavee, Pak Nam Pho, Mueang Nakhon Sawan, Nakhon Sawan, 60000, Thailand.
Eye (London, England)
|March 13, 2024
概括
在甲状腺眼病 (TED) 中的视觉神经病变 (DON) 诊断可以使用特定的计算机断层扫描 (CT) 参数来改进. 纽根特分数和巴雷特指数 (BI) ≥50%是最有效的迅速视力保护治疗.
科学领域:
- 眼科医生 眼科 眼科
- 放射学 放射学是一门学科.
- 内分泌学 在内分泌学.
背景情况:
- 甲状腺视觉神经病变 (DON) 在甲状腺眼病 (TED) 中显著影响视力.
- 早期诊断和治疗对于保持视力至关重要.
- 计算机断层扫描 (CT) 参数用于DON诊断,但其诊断性能缺乏共识.
研究的目的:
- 系统地审查和对成年TED患者DON轨道CT参数的诊断性能进行元分析.
- 为了确定诊断DON的最可靠的CT参数.
主要方法:
- 对评估DON的轨道CT研究的系统审查和元分析.
- 在Medline,PubMed,Scopus和EMBASE数据库中搜索到2023年7月.
- 分析了巴雷特指数 (BI) 的诊断测试准确性 (DTA),通过上层轨道裂 (SOF) 脱落脂肪,上层眼膜静脉扩张 (SOVD) 和努根特得分.
主要成果:
- 纽根得分显示了最高的诊断能力 (logDOR 2.64).
- 巴雷特指数 (BI) ≥50%也是一个重要的指标 (logDOR 1.97).
- 通过SOF和SOVD的脂肪落显示出较低的诊断灵敏度.
结论:
- 纽根特分数和BI ≥50%是DON的重要诊断参数.
- 这些参数比SOF脂肪脱落或SOVD更可靠.
- 优先考虑这些CT参数可以导致早期治疗和改善DON患者的视觉结果.
相关概念视频
01:25Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
01:27Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:28Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...