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由ATF5诱导的线粒体UPR通过与线粒体合作减轻椎间盘退化

Wen-Ning Xu1,2, Huo-Liang Zheng2, Run-Ze Yang3

  • 1Department of Spinal Surgery, Orthopedic Medical Center, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China.

Cell biology and toxicology
|March 13, 2024
PubMed
概括

线粒体展开的蛋白质反应 (UPRmt) 在椎间盘退化 (IVDD) 中升高. 用NR激活UPRmt显示出通过促进细胞和减少细胞死亡来治疗IVDD的前景.

关键词:
在5f5的时间里,椎间盘退化 椎间盘退化线粒体展开的蛋白质反应反应线粒细胞衰变 (mitophagy) 是一种细胞衰变的过程.粉红色的1 粉红色的1

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