对Eclipse和RayStation的比较研究多标准优化基于前列腺放射治疗治疗计划质量优化质量
John Y K Wong1,2, Vincent W S Leung1, Rico H M Hung2
1Department of Health Technology and Informatics, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China.
Diagnostics (Basel, Switzerland)
|March 13, 2024
概括
这项研究发现,Eclipse基于MCO的前列腺放射治疗计划与RayStation相比,提供了更优质的质量. 在理想计划和可交付计划之间观察到差异,影响了剂量测量结果.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
- 癌症治疗方法 癌症治疗方法
背景情况:
- 放射治疗计划系统中的多标准优化 (MCO) 功能旨在提高治疗计划的质量.
- 像Eclipse和RayStation这样的商业系统提供MCO,但对前列腺癌缺乏直接比较.
研究的目的:
- 为了比较使用Eclipse和RayStation中的MCO函数生成的前列腺放射治疗计划的质量.
- 评估帕雷托最佳计划和最终可交付计划之间的差异.
- 评估前列腺癌放射治疗中最终可交付计划的剂量影响.
主要方法:
- 25名前列腺癌患者的CT数据集被用于Eclipse (v16.1) 和RayStation (v12A) 的规划.
- 作为权衡标准,MCO规划的重点是PTV76 D98% (76 Gy处方) 和直肠D50%.
- 通过比较帕雷托最佳与最终可交付计划,并通过t测试评估剂量计参数 (PTV,直肠剂量,PTV HI,CI) 来评估计划质量.
主要成果:
- 两种系统在帕雷托最佳计划和最终交付计划之间都存在差异.
- 埃克利普斯显示 -0.89% (PTV D98%) 和 -2.49% (直肠 D50%) 的差异;雷电站显示3.56% (PTV D98%) 和 -1.96% (直肠 D50%).
- 与RayStation (70.43 Gy, 0.11, 0.87, 51.65 Gy) 相比,Eclipse计划在统计学上显示出更高的PTV D98%,HI,CI,以及较低的平均直肠剂量 (76.07 Gy, 0.06, 1.05, 39.36 Gy).
结论:
- 与RayStation相比,Eclipse的MCO功能导致更高质量的前列腺放射治疗计划.
- 在两种系统之间发现了显著的剂量测量差异,有利于Eclipse的目标覆盖和危险器官节省.
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