目前和新兴的辐射疗法选项对于Uveal黑色素瘤
Oleksii Semeniuk1, Esther Yu1, Mark J Rivard1
1Department of Radiation Oncology, Warren Alpert Medical School, Brown University and Rhode Island Hospital, Providence, RI 02903, USA.
Cancers
|March 13, 2024
概括
对于毛膜性黑色素瘤,胸膜疗法和核切除提供了与中型瘤相似的存活率. 节省眼睛的支臂疗法技术已经进步,各种辐射方式显示出患者治疗的不同属性.
科学领域:
- 眼科医生 眼科 眼科
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
背景情况:
- 卵巢黑色素瘤是一种罕见的眼内恶性瘤.
- 传统的治疗包括去核,但人们正在寻求节省眼睛的选择.
- 合作眼睛黑色素瘤研究 (COMS) 提供了关键的生存数据.
研究的目的:
- 审查和比较各种辐射治疗方式,用于皮膜黑色素瘤.
- 检查不同方法的剂量测量特性,准能力和临床结果.
- 以患者和病变特征为基础,为最佳治疗选择提供信息.
主要方法:
- 检查基疗法技术 (低剂量率,高剂量率,光子/β发射器,斑块设计).
- 检查外部光束放射治疗 (线性加速器,质子疗法,马立体性放射外科手术).
- 对剂量测量属性的分析,准准确度和患者的结果.
主要成果:
- 在中等瘤中,支臂疗法提供了眼睛的保护,其存活率与化相比较.
- 已经开发出多种不同的支臂疗法方法 (例如,不同的放射性核素,种子,剂量率).
- 外部光束放射治疗的选择,如质子疗法和立体射线外科手术也可用.
- 每种模式都有独特的剂量测量和准能力.
结论:
- 没有一种单一的辐射方式对所有阴道黑色素瘤病例来说是普遍最佳的.
- 选择治疗应该考虑个体患者的因素和特定的瘤特征.
- 对剂量测量特性和临床结果的持续评估对于推进皮膜黑色素瘤管理至关重要.
相关概念视频
01:27Tumor Immunotherapy
524
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
524
01:30Skin Cancer
4.1K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.1K
02:57Targeted Cancer Therapies
7.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.6K
02:49Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K