自体主导多囊性病:外干涉
Matteo Righini1,2, Raul Mancini2, Marco Busutti2
1Nephrology and Dialysis Unit, Santa Maria delle Croci Hospital, AUSL Romagna, 48121 Ravenna, Italy.
International journal of molecular sciences
|March 13, 2024
概括
自体主导多囊性病 (ADPKD) 影响脏以外的多个器官,包括肝脏,胰腺和大脑. 本综述详细介绍了对ADPKD系统性和外表现的最新理解.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 遗传学 遗传学是一种遗传学.
- 内部医学 内部医学
背景情况:
- 自体主导多囊性病 (ADPKD) 是最常见的遗传性病.
- ADPKD是一种系统性疾病,影响脏以外的器官,包括肝脏,胰腺,大脑,血管系统,胃肠道,骨和心脏门.
研究的目的:
- 提供关于ADPKD外皮表现现的当前知识的全面概述.
- 为了突出非性并发症在ADPKD患者中因生存率增加而日益增长的临床重要性.
主要方法:
- 本综述综合了关于ADPKD系统性和外表现现的当前文献.
- 它专注于影响各种器官的囊性和非囊性并发症.
主要成果:
- 肝脏干扰是最常见的外表现,显著影响生活质量.
- 血管异常,特别是动脉高血压,对于患者的预后和心血管健康至关重要.
- 心脏膜和骨疾病也很常见,影响ADPKD的临床过程.
结论:
- 外表表现是ADPKD管理的一个关键方面.
- 了解和解决这些系统性并发症对于改善患者的治疗结果和生活质量至关重要.
关键词:
在 ADPKDD 中,在PLD PLD中使用.骨疾病 骨疾病纤维病变 (ciliopathy) 是一种纤维病变.囊性病是脏疾病.外囊性囊性卷入症.遗传学 遗传学 遗传学 遗传学 是一个内动脉瘤 内动脉瘤更多相关视频
07:35Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
11.5K
09:40Isolation, Characterization, And High Throughput Extracellular Flux Analysis of Mouse Primary Renal Tubular Epithelial Cells
Published on: June 20, 2018
17.5K
相关概念视频
Renal Corpuscle
2.1K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
2.1K
Nephrons
2.4K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
2.4K
Internal Anatomy of the Kidney
1.6K
The kidneys are essential organs in the human body, performing a myriad of tasks that maintain homeostasis and overall health.
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
1.6K
External Anatomy of the Kidney
1.1K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
1.1K
Kidney Structure
69.6K
The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.
69.6K
Renal Drug Excretion: Overview
155
As primary excretory organs, the kidneys maintain homeostasis by removing waste substances from the bloodstream. They comprise over a million units called nephrons, which serve as the kidney's functional units.
A nephron consists of two primary structures: the renal corpuscle and the renal tubule. The renal corpuscle contains the glomerulus, a network of capillaries where the first step of renal excretion, glomerular filtration, occurs. Blood pressure forces water, ions, and small molecules...
A nephron consists of two primary structures: the renal corpuscle and the renal tubule. The renal corpuscle contains the glomerulus, a network of capillaries where the first step of renal excretion, glomerular filtration, occurs. Blood pressure forces water, ions, and small molecules...
155
