西BECLIN1

Tillmann Bork1, Camila Hernando-Erhard1, Wei Liang1,2

  • 1Department of Medicine IV, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.

概括

减少的BECLIN1 (ATG6) 蛋白质使脏对西斯素敏感,增加ER压力和急性损伤 (AKI). 这表明BECLIN1可以独立于自细胞对ER压力进行保护,为AKI提供新的治疗点.

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