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Updated: Jul 1, 2025

Author Spotlight: Decoding DNA Repair by Extrachromosomal NHEJ Assay and HR Assays
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Author Spotlight: Decoding DNA Repair by Extrachromosomal NHEJ Assay and HR Assays

Published on: February 2, 2024

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在患有类风湿性关节炎的患者中,DNA双链断裂的低效修复和HRR和NHEJ修复基因的常见多态性之间的关联

Grzegorz Galita1, Joanna Sarnik2, Olga Brzezinska2

  • 1Department of Clinical Chemistry and Biochemistry, Medical University of Lodz, 92-215 Lodz, Poland.

International journal of molecular sciences
|March 13, 2024
PubMed
概括

类风湿性关节炎患者显示DNA双链断裂 (DSB) 修复效率受损. RAD50和RAD51B基因的遗传变异,以及基因表达的增加,与类风湿性关节炎中这种DNA修复缺陷有关.

关键词:
在DNA双链断裂过程中,修复DNA的修复DNA的修复在RAD50中使用RAD50.在RAD51B中,使用了RAD51B.彗星测试试验 彗星测试试验类风湿性关节炎是一种类风湿性关节炎.一个核酸的多态性.

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