O26 多糖类作为肠病原性E.中关键参与者 大肠杆菌的免疫逃避和疫苗开发

Thiago Jordão da Silva Lemos1, Herbert Guimarães de Sousa Silva1, José Osvaldo Previato2

  • 1Laboratório de Bacteriologia, Instituto Butantan, Avenida Vital Brasil, 1500, São Paulo 05503-900, SP, Brazil.

概括

肠病原性大肠杆菌 (EPEC) 在囊中使用O26多糖化合物进行免疫逃避,阻碍补充和巨细胞的反应. 反O26抗体中和这种保护和EPEC粘附,表明O26多糖类作为疫苗抗原.

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