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Updated: Jul 1, 2025

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罗氏/MRTF/SRF转录通路的抑制剂调节线粒体功能

Pankaj Patyal1, Xiaomin Zhang1, Ambika Verma1

  • 1Donald W. Reynolds Department of Geriatrics and Institute on Aging, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

Cells
|March 13, 2024
PubMed
概括

新型的氧化-硫乙烯化合物CCG-203971和CCG-232601可以抑制Rho/MRTF/SRF信号传输. 这些化合物通过改变基因表达来向线粒体功能,为涉及异常生物能学的疾病提供潜在的治疗策略.

关键词:
在Rho/MRTF/SRF中使用.通过乙化处理.生物能源生物能源学基因组-4 基因组-4 基因组-4线粒体中的线粒体.氧化应激是一种氧化应激.

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