相关实验视频

Updated: Jul 1, 2025

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
08:19

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo

Published on: July 20, 2019

6.0K

尼古丁胺胺利博酸增加人体巨细胞通过SIRT3-介导的前列腺素E2信号传输迁移

Jing Wu1, Maximilian Bley1, Russell S Steans1

  • 1Laboratory of Mitochondrial Biology and Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health, Bldg. 10-CRC, Room 5-3342, 10 Center Drive, Bethesda, MD 20892, USA.

Cells
|March 13, 2024
PubMed
概括

尼古丁胺基化物 (NR) 通过增加CCR7表达和PGE2合成,通过SIRT3和COX-2调解来增强巨细胞迁移. 这一途径显示了慢性伤口愈合疗法的潜力.

关键词:
提升NAD+的增强作用在SIRT3中,SIRT3是最重要的.化学反应的化学作用.巨细胞迁移的情况尼古丁胺胺里化物的前列腺素E2E2的前列腺素.

更多相关视频

Reprograming Model of Human Monocyte-derived Macrophages for In-vitro Assays08:37

Reprograming Model of Human Monocyte-derived Macrophages for In-vitro Assays

Published on: April 18, 2025

332
A Macrophage Reporter Cell Assay to Examine Toll-Like Receptor-Mediated NF-kB/AP-1 Signaling on Adsorbed Protein Layers on Polymeric Surfaces07:55

A Macrophage Reporter Cell Assay to Examine Toll-Like Receptor-Mediated NF-kB/AP-1 Signaling on Adsorbed Protein Layers on Polymeric Surfaces

Published on: January 7, 2020

7.4K

相关概念视频

NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The...
7.4K