控制营养状况 (CONUT) 评分和身体组成,住院老年患者的炎症和虚弱之间的关联
Aurelio Lo Buglio1, Francesco Bellanti1, Daniela Francesca Pia Carmignano1
1Department of Medical and Surgical Sciences, University of Foggia, Viale Pinto 1, 71122 Foggia, Italy.
Nutrients
|March 13, 2024
概括
控制营养状况 (CONUT) 评分识别了老年患者的营养不良. 高CONUT分数与炎症,体质不佳和脆弱相关,使其成为一种有价值的查工具.
科学领域:
- 老年病的医生 老年病的医生
- 临床营养学 临床营养学
- 生物标志物 生物标志物
背景情况:
- 控制营养状况 (CONUT) 评分是评估营养状况和预测结果的验证工具.
- 营养状况,炎症和身体成分是老年患者健康的关键因素.
- 在住院的老年人群中,虚弱是令人担忧的一个重要问题.
研究的目的:
- 评估CONUT得分,炎症标志物和身体组成之间的关联.
- 为了确定CONUT评分在诊断住院老年患者的虚弱风险方面的有效性.
主要方法:
- 对361名住院的老年患者进行了回顾性分析.
- 根据患者的CONUT分数,患者被分为三组.
- 使用了相关性分析和接收器运行特征 (ROC) 曲线.
主要成果:
- 较高的CONUT分数与炎症标志物 (ESR,CRP,NLR,MPV,费里丁) 和不利的身体组成 (较低的骨肌肉质量,较高的脂肪质量) 的升高有关.
- 该CONUT得分与炎症,抑郁症 (GDS-SF) 和脂肪质量正相关.
- 与营养评估 (MNA),认知功能,功能状态 (ADL,IADL,Barthel指数) 和瘦肉质量 (FFM,MM) 观察到负相关性.
- 患有高CONUT分数的患者的脆弱性患病率显著更高,通过ROC分析识别的准确性很高.
结论:
- 在住院的老年人中,CONUT评分与促炎状态和不良的身体组成有关.
- 该CONUT得分作为一个有效的工具来识别这个患者群体的脆弱性.
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