比利时儿童的维生素D状况:一项区域研究
Louise Van de Walle1, Yvan Vandenplas2, Jaan Toelen1,3
1Department of Development and Regeneration, University of Leuven, 3000 Leuven, Belgium.
Nutrients
|March 13, 2024
概括
大多数儿童 (超过80%) 维生素D水平不足,青少年受影响最严重. 目前比利时关于补充维生素D的指导方针可能需要对0-18岁儿童进行修订.
科学领域:
- 儿科 儿科 儿科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 维生素D缺乏是导致儿童骨生长受损和营养的主要原因.
- 评估维生素D状态对于儿科骨健康至关重要.
- 了解患病率可以为公共卫生策略和补充指南提供信息.
研究的目的:
- 评估广泛的儿科年龄范围 (0-18岁) 的维生素D状况.
- 确定影响儿童维生素D水平的人口和季节因素.
- 根据目前比利时关于维生素D补充剂的健康建议提供信息.
主要方法:
- 在2014年至2021年期间收集的14887个儿科血液样本的回顾性分析.
- 维生素D水平分为严重缺乏 (<12 ng/mL),不足 (12-20 ng/mL),边界 (20-30 ng/mL) 和充足 (>30 ng/mL) 的类别.
- 统计分析以评估与年龄,性别和季节的关联.
主要成果:
- 显著的大多数 (71%以上) 的儿童表现出严重缺乏,不足或边界维生素D水平.
- 青少年 (13-18岁) 的严重维生素D缺乏率最高 (24.9%).
- 与冬季/春季相比,夏季/秋季的维生素D水平显著更高;没有发现性别相关性.
结论:
- 维生素D缺乏和不足的高患病率存在于0-18岁的儿童中,特别是7岁以上的儿童.
- 超过80%的研究儿童没有达到推的30 ng/mL的维生素D充足度值.
- 目前比利时的建议是停止在6岁时服用补充剂,鉴于缺乏症的高患病率,需要重新评估.
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