在人类一生中探索肠道微生物组和身体组成之间的动态关系:系统性审查
Ifigeneia Komodromou1, Eleni Andreou1,2, Angelos Vlahoyiannis1,2
1Department of Life Sciences, School of Life and Health Sciences, University of Nicosia, 2417 Nicosia, Cyprus.
Nutrients
|March 13, 2024
概括
在超重个体和运动员中,肠道微生物组的组成不同. 超重的个体表现出减少的细菌菌体和增加的菌体,而运动员则表现出相反的情况,影响身体成分.
科学领域:
- 微生物组研究的研究.
- 人类生理学 人类生理学
- 营养科学 营养科学
背景情况:
- 肠道微生物群在宿主新陈代谢和健康中起着至关重要的作用.
- 了解人类一生中的肠道微生物群变化及其与人体组成的联系对于有针对性的健康干预至关重要.
研究的目的:
- 在人类一生中,系统地审查和识别不同的肠道微生物群概况.
- 调查这些肠道微生物组资料与各种身体组成参数之间的相关性.
主要方法:
- 在PubMed,Scopus和Cochrane数据库的系统文献搜索 (开始至2022年3月).
- 包括60项研究进行全面分析.
- 肠道微生物组组成与身体组成指标的相关性分析.
主要成果:
- 与正常体重的个体相比,超重个体的α-多样性降低,Bacteroidetes减少,Firmicutes增加.
- 脂肪质量和腰围与Firmicutes正相关,与Bacteroidetes负相关.
- 瘦体质和肌肉质量与细菌菌体有积极的相关性,这些模式在运动员中更为明显.
结论:
- 肠道微生物组的组成在所有年龄段的超重个体和运动员之间存在显著差异.
- 超重个体倾向于增加Firmicutes和减少Bacteroidetes,而运动员则显示相反的模式.
- 需要进一步的研究来阐明饮食,身体组成和整个生命的肠道微生物组之间的动态相互作用.
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