预测患有心力衰竭的患者在入院时使用体重指数和体重减轻的死亡风险
Yuria Ishida1,2, Keisuke Maeda2,3,4, Kenta Murotani5,6
1Department of Nutrition, Aichi Medical University Hospital, Nagakute, Aichi, Japan.
Annals of geriatric medicine and research
|March 13, 2024
概括
低体重指数 (BMI) 和心力衰竭 (HF) 患者的体重减轻与死亡风险增加有关. 这项研究强调了体重和BMI在HF管理中的预后重要性.
科学领域:
- 心脏病学 心脏病学
- 临床营养学 临床营养学
- 公共卫生 公共卫生
背景情况:
- 身体质量指数 (BMI) 和心力衰竭 (HF) 患者入院时体重变化的预后影响仍然不完全理解.
- 现有研究尚未完全阐明BMI和体重波动对HF患者结果的综合影响.
研究的目的:
- 研究入院身体质量指数 (BMI) 和体重变化对被诊断为心力衰竭 (HF) 患者的死亡风险的独立和综合影响.
主要方法:
- 一项回顾性队列研究涉及4,862名日本患有HF的患者,经过99个月的跟踪.
- 使用立方体和薄板光滑线分析来评估BMI,百分比体重变化 (每半年计算) 和全因死亡率之间的关联.
- 数据来源于真实世界的日本数据库.
主要成果:
- 在BMI和死亡危险比率 (HR) 之间观察到负相关性,较低的BMI (例如18.5kg/m2) 与较高的死亡风险相关.
- 体重减轻表明死亡率HR增加的趋势,每6%的体重变化率下降与死亡风险增加1.1倍相关.
- 薄板脊柱分析证实,较低的BMI与1年和2年死亡率的更高几率比率 (OR) 有关,不论体重变化如何.
结论:
- 入院时的低BMI是心力衰竭患者死亡风险增加的重要预测因素.
- 体重减轻,独立于患者的BMI,也与HF患者死亡率更高的可能性有关.
- 这些发现强调了监测BMI和体重变化对于心力衰竭管理的预后的重要性.
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