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美国疾病预防控制中心 (CDC) 针对孕期暴露婴儿和儿童的新型C型肝炎病毒检测建议:迈向消除C型肝炎的一步
Lakshmi Panagiotakopoulos1, Kathryn Miele2, Emily J Cartwright1
1Division of Viral Hepatitis, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Journal of women's health (2002)
|March 13, 2024
概括
新的2023年CDC指南建议在2-6个月的婴儿中使用NAT对HCVRNA进行型肝炎C病毒 (HCV) 检测. 这种早期检测可以改善患有围产期HCV感染的儿童的护理,推进消除工作.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 肝炎C病毒 (HCV) 感染是肝硬化,肝癌和过早死亡的主要原因,在怀孕期间越来越普遍.
- 周产期暴露是 HCV 在婴儿和儿童中最常见的传播途径.
- 以前的测试建议 (18个月的抗HCV) 导致许多儿童由于失去随访而未被诊断.
研究的目的:
- 描述更新的美国疾病控制和预防中心 (CDC) 关于测试婴儿和婴儿的指导方针,这些婴儿和儿童在产前暴露于HCV.
- 突出转向早期检测的转变,以及与护理周产期获得的HCV感染的联系.
- 强调这些更新的建议如何支持国家型肝炎消除目标.
主要方法:
- 该报告审查了2023年CDC关于围产期HCV检测的指导方针.
- 它侧重于推的核酸测试 (NAT) 检测HCV核糖核酸 (RNA) 在2-6个月龄.
- 该新策略的成本效益与以前的方法相比被考虑.
主要成果:
- 新的指导方针建议在2-6个月的婴儿中使用NAT检测HCVRNA.
- 这种策略在识别感染儿童方面比之前的18个月的抗HCV测试更有效.
- 通过NAT对HCVRNA的早期识别有助于及时连接到护理.
结论:
- 更新的CDC指南代表了识别和管理围产期HCV感染的重大进展.
- 早期婴儿检测可以改善儿童的健康状况,并支持消除C型肝炎的更广泛目标.
- 在怀孕期间整合HCV查和早期婴儿检测对于全面的产周护理至关重要.
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